ABSTRACT
Human infection with avian influenza A (H7N9) is an acute contagious respiratory disease. Acute respiratory distress syndrome (ARDS) is a common complication in patients with severe avian influenza A (H7N9), for whom mechanical ventilation (MV) is an important supportive method. A patient, suffered from severe avian influenza A (H7N9) and complicated with ARDS, was admitted to the Second Affiliated Hospital of Guizhou Medical University in January 2017. With very intensive care for oxygenation, respiration and consciousness, and monitoring, she was successfully cured by comprehensive managements, among which noninvasive mechanical ventilation (NIV) was the major respiratory support method. The result demonstrate that, in patients with conscious state, satisfied expectoration ability and relatively good cooperation, and with close observation of oxygenation and respiratory rate, NIV may be accepted as an effective method for patient with ARDS caused by severe avian influenza A (H7N9).
ABSTRACT
Exosomes are extracellular vesicles with a diameter of 30-100 nm formed during the processes of "endocytosis-fusion-exocytosis".Exosomes can be released by various types of cells and may carry important biological molecules,such as lipids,proteins,and nucleic acids.They are also involved in signal transduction and exchange of substances between cells and can regulate the physiological and pathological processes in various systems.They also play an important role in liver diseases,including liver cancer,viral hepatitis,liver fibrosis,and alcoholic and non-alcoholic fatty liver disease.This article reviews the research advances in exosomes in liver diseases.
ABSTRACT
Exosomes are extracellular vesicles with a diameter of 30-100 nm formed during the processes of "endocytosis-fusion-exocytosis".Exosomes can be released by various types of cells and may carry important biological molecules,such as lipids,proteins,and nucleic acids.They are also involved in signal transduction and exchange of substances between cells and can regulate the physiological and pathological processes in various systems.They also play an important role in liver diseases,including liver cancer,viral hepatitis,liver fibrosis,and alcoholic and non-alcoholic fatty liver disease.This article reviews the research advances in exosomes in liver diseases.
ABSTRACT
Objective To investigate the value of combined therapy for hand post-burn scars.Methods We retrospectively analyzed 78 hands post-burn scars in 46 cases from 2007 to 2011.A mong them,scar contracture releasing,scar excision,free skin grafting and fixation with Kirschner's pins were performed in 38 hands,scar excision and regional flat transfer were performed in 18 hands,scar excision and skin grafting were performed in 18 hands,abdominal expanded flap transplantation and scar excision were performed in 4 hands.All patients received elastic sleeve pressure therapy,sili cone gel for external application and function training.Within six months after the operation,52 hands received drug delivery by wax therapy,16 hands incision with scar proliferation received drug injection into scar.We followed up all patients from half a year to three years after the treatment to observe the recovery of the appearance and function of the hands.Results We mainly chose surgery,elastic sleeve pressure therapy,silicone gel for external application,drug injection into scar,wax therapy,function training and so on treating the hand post-burn scars and found that the joins deformities caused by scar contracture were largely or totally corrected.The function and appearance were satisfying.Conclusions It is a good method to treat hand scars by surgery and post-surgery combined physical rehabilitation therapy,which deserves to popularization.